IVF Replacement for NPO Deficit

Formula: IV fluid replacement for NPO deficit

2 mL × W × H

• W = Weight in kilograms (kg)
• H = Hours

IV fluid replacement for NPO deficit = 2 milliliter/kilogram (2mL/kg) for each hour NPO prior to surgery. Replace 50% of deficit within the first hour of surgery with the remaining 50% being replaced over the next 2 hours. If the patient stayed in the hospital overnight with an IV infusing while NPO, subtract this amount from the NPO deficit.

Example

Replace the NPO deficit for a patient who weighs 50 kg who has been NPO for 10 hours prior to surgery?

• NPO deficit = 2mL × 50 kg × 10 Hrs
• NPO deficit = 1,000 mL
• ½ NPO deficit = 500 mL

Answer: Give 500 mL the first hour then 250 mL the second hour and another 250 mL the 3^rd hour. If in this example, the patient stayed in the hospital overnight with an IV infusion at 100 mL/hr while NPO, all their NPO deficit (1 liter) would already be replaced.